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PCOS and Infertility – There Are Solutions to This Terrible Combination

PCOS, which is an acronym for polycystic ovary syndrome, is a hormonal disorder associated with the human body’s insulin resistance. It is a medical condition that increases the body’s insulin sensitivity, or results in increased insulin production. To overcome this problem, the female body secretes androgens, which are the hormones needed to maintain male characteristics. Although PCOS can cause diabetes, PCOS and infertility are also interconnected.

PCOS Causes Infertility

During a woman’s normal sexual cycle, small collections of cells known as follicles develop in the ovaries. Although each of these will contain an egg, only one of these will develop into a fertilized egg. When the egg matures, there will be a surge of LH, or luteinizing hormone, which triggers ovulation, which is the process by which the mature egg is released. For women with PCOS, the follicles fail to develop properly due to a lack of sufficient female hormones. Some follicles become cysts, and sometimes none can develop into mature eggs.

In the image produced by scanning, these follicles appear as a group of pearls covering the ovary. Infertility treatment becomes necessary because, the absence of ovulation results in the thickening of the lining of the uterus due to lack of progesterone. Progesterone is normally produced during the rupture of ovarian follicles.

Early Detection of PCOS and its Symptoms

Irregular periods are a symptom of PCOS. The problem can increase with age and can result in irregular ovulation or a complete lack of ovulation. Although 5% to 10% of women of reproductive age may experience this problem, the condition is diagnosed in only about a quarter of them.

Although PCOS and infertility have a strong connection, some women manage to get pregnant even between irregular ovulations. While for some women, the only symptom of PCOS may be irregular periods, others may show symptoms such as type 2 diabetes, high insulin levels, hair loss, hair growth on the chest or back or face, or unexplained weight gain. can be explained.

PCOS solution

It is clear that a woman with PCOS fails to conceive because she fails to ovulate. The simplest infertility treatment for this problem is to correct the hormonal imbalance by losing weight. In the case of drug therapy, the drug Metformin is recommended for women with PCOS as long as they do not have diabetes. This drug can make the body more receptive to insulin absorption, without actually lowering blood sugar.

Another drug used for the treatment of PCOS-related infertility is Clomid. Clomid works by blocking the brain’s estrogen receptors. When the receptors fail to register the presence of estrogen, the brain remains under the illusion that the body’s estrogen content is low. This is thought to produce more FSH (follicle stimulating hormone), and LH (luteinizing hormone), which help in ovulation. Despite this, pregnancy is seen in only 30% to 40% of women who have used Clomid.

Other treatments for PCOS are IVM or in vitro fertilization, and IVF or in vitro fertilization. In containers, immature eggs are removed from the body, preserved in the laboratory, and then fertilized. In IVF, a fully mature egg is fertilized outside the body and then implanted into the uterus. In IVF, before a mature egg is fertilized, medication is often required to ensure the proper growth of the egg to maturity. With IVM, the level of medication required is less because the egg matures outside the body. So this procedure is more suitable for women whose body is less responsive to drugs.

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