How Long Does Metformin Take To Work For Weight Loss Insulin Resistance – How Does Metformin Help Those With PCOS?

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Insulin Resistance – How Does Metformin Help Those With PCOS?

Most women with PCOS have weight problems (overweight, have gained a large amount of weight in a short time). For some reason, despite their diet and exercise program, they STILL gain weight and find it difficult to lose weight at all. This is due to something called Insulin resistance. This is a condition where large amounts of insulin are needed to get blood glucose transferred into the cells. Insulin resistance can cause weight problems, irregular cycles/Infertility, heart disease, diabetes and some cancers, and is more of a health concern for women than men. The most common drug used to treat insulin resistance is Metformin (also known as Glucophage, or Glucophage XR).

Metformin helps control your insulin levels. Studies also show that Metformin can help reduce excess facial hair, induce ovulation and regulate the menstrual cycle.

Some of the benefits of Metformin include: (note, not all women who take Metformin will experience these benefits, everyone responds differently to the drug):

  • Increases chances of ovulation
  • Reduces excess facial/body hair
  • Cycle rules
  • Delaying the onset of Adult-Onset Diabetes
  • Reduce your chances of getting Gestational Diabetes (Diabetes during pregnancy)
  • Reduces your chances of miscarriage (PCOS users have an increased rate of miscarriage)
  • Weight loss (with healthy diet and exercise)

Disadvantages of using Metformin:

  • Most patients complain of strong gastrointestinal side effects (abdominal cramps, diarrhea, gas, bloating, nausea and vomiting)
  • Metformin can also increase levels of homocysteine ​​​​​​(this is an amino acid found in the blood), which puts a person at risk for atherosclerosis (or fatty deposits in the blood vessels).
  • Long-term use of Metformin can cause B12 malabsorption, which can cause anemia
  • Lactic acidosis: Lactic acid is a metabolic byproduct that can be toxic if it accumulates faster than it is eliminated. It is very serious and can be fatal. The symptoms are rapid breathing, irregular pulse, weakness, drowsiness, and muscle pain. (If you are taking Metformin and experience any of these symptoms, call your doctor immediately, or go to the nearest emergency room.

Those with pre-existing conditions should talk to their doctor before starting Metformin. If you have liver or kidney problems, or you drink alcohol inappropriate take Metformin as this may increase the chance of Lactic Acidosis.

Again, it’s up to you and your doctor to review the benefits and side effects of all medications (don’t be afraid to ask LOTS of questions!). Then you and your health care provider (whether Primary, OB/GYN or RE) can determine the best treatment method for your situation.

Do your own research!! It is in your best interest to research a drug (any drug!) before putting it into your body, ESPECIALLY if you have a pre-existing condition.

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